Researchers have reported a link between exposure to BPA among mothers in early pregnancy and wheezing in their infants later on, a development that could add to a rising tide of health concerns over the widely used chemical.
Children whose mothers had higher levels of BPA in their urine early in pregnancy were twice as likely to be wheezing at six months of age than infants whose mothers had lower BPA levels, the researchers said.
However, while higher concentrations of BPA at 16 weeks of pregnancy were associated with wheezing, the same concentrations at 26 weeks or at birth were not. “This suggests that there are periods of time during pregnancy when the fetus is more vulnerable,” lead researcher Dr. Adam Spanier, a professor of pediatrics at the Penn State College of Medicine, said in an article on the school’s website. “Exposure [to BPA] during early pregnancy may be worse than exposure in later pregnancy.”
BPA, or bisphenol A, is widely used in plastics and in food and beverage containers. Researchers have linked it to problems ranging from breast and prostate cancer to infertility and obesity. It is being investigated by U.S. health authorities and, in October, the Canadian government declared BPA a toxic substance.
Previous studies have suggested that BPA exposure causes asthma in mice. The new study by researchers at Penn State and Cincinnati Children’s Hospital Medical Center, which included 367 pairs of mothers and infants, is the first to evaluate a link between BPA and wheezing. The researchers’ findings were presented in Denver at the Pediatric Academic Societies’ annual meeting ending today.
A spokesman for the American Chemistry Council told CNN that the study “is inherently incapable of establishing a cause-effect relationship between any causative agent and wheezing. The statistical associations reported in this study have not been verified or corroborated by any other study on BPA, which is one of the best tested substances in commerce.”
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