A diabetes and weight-loss drug used by millions in France may have killed at least 500 people, according to the country’s drug safety body.
Mediator, made by French pharmaceutical company Servier, had been on the market since 1976 but was pulled last year after France’s drug safety body Afssaps said it did little for diabetes and might cause heart valves to dangerously thicken.
In addition to hundreds of deaths, epidemiologists said the drug, taken by an estimated 3 million in France, likely caused 3,500 others to be admitted to the hospital.
Some experts said the ban was applied too slowly in the country, despite long-standing knowledge of its potentially deadly side effects. The drug was pulled from Italy and Spain in 2005. It was also banned in the U.S.
”Why didn’t they do it earlier [in France]?” asked Dr. Irene Frachon, an expert on Mediator’s dangers, according to Australian media outlet The Age.
France’s health minister, Xavier Bertrand, advised anyone who had taken the drug to see a doctor.
Servier is already facing four lawsuits over the drug but said the heart valve condition observed in some patients should not be attributed to the medicine.
In September, European regulators pulled another diabetes drug from the market — Avandia, a drug linked to an increase in heart attacks and under tight restrictions in the U.S.
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